Isoflavone Research Initiative

    Deutsch (DE-CH-AT)English (United Kingdom)

Isoflavones in health

Confessions of a Shopaholic
What are isoflavones?
Isoflavones are a type of phyto-esterogens found in soy and other plants. Read more...
Nothing like the holidays
Safety
Isoflavones have a very good safety profile. Read the details.
How to lose Friends and Alienate people
Clinical effects
Isoflavones may be beneficial in a range of health problems. Read the details.

Subscribe to Isoflavone News

Enter your email address:

Welcome to the Isoflavone Research Initiative

Isoflavones are secondary plant metabolites typically found in the diet. They are held responsible for a multitude of beneficial effects on health. The effects have been examined in more than 10,000 studies. Isoflavone-containing plants are primarily soy and red clover, but also alfalfa contains these micronutrients, which have been compared with vitamins by some scientists.

The Isoflavone Research Initiative is exclusively focusing on this singular substance group, and presents the most recent findings related to the benefits, but also the safety of application of isoflavones.

 

What are isoflavones ?

Isoflavones are typical constituents of certain food plants from human nutrition and animal feeding, such as soy, red clover or alfalfa (lucerne).soy isoflavones Their chemical structure resembles that of the flavones, typical contrituents of many fruits and legumes - the syllable "iso" tells the chemist that a part of the molecule is differently attached.

The best-known isoflavones are genistein, daidzein and glycitein from soy and red clover, and biochanin A and formononetin from red clover. The latter are transformed to the former in the human gastrointestinal tract.

Read more...
 

Study data support phytotherapy as an alternative to HRT

Recent publications do not only contribute to the question of efficacy and safety of application of isoflavones, but also to the choice of a safe and efficacious daily dose. These questions were the focus of a recent clinical perspective paper of Dr. Bernd Kleine-Gunk, member of the Isoflavone Research Initiative.

Dr. Kleine-Gunk concludes that - compared with placebo - the efficacy of isoflavones against menopausal complaints is by now well-established with a daily intake above 50 mg.  Similarly, safety at hormone-sensitive tissues can by now be accepted as given up to doses by far exceeding 100 mg per day.

Reference:

Bernd Kleine-Gunk: Neue Studiendaten stützen Phytotherapie als HRT-Alternative. gynäkologie + Geburtshilfe (12): 16-17 (2010)

The full text (in German) is available at www.gynundgeburtshilfe.de

 
  • Clinical use

  • Safety info

Confessions of a Shopaholic
Isoflavones may be beneficial for menopausal complaints, elevated serum lipids, osteoporosis, inflammatory conditions, cancer and prevention of cognitive decline.
Confessions of a Shopaholic
Isoflavones have a very good safety profile.

Latest News

Isoflavone Research Initiative

sojaIn this place the Isoflavone Research Initiative focusses on this singular group of plant constituents, and presents the latest findings regarding benefits and safety of application of isoflavones.
You are here: Home